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Review Article
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- Identification and infection control of carbapenem-resistant Enterobacterales in intensive care units
- Jongyoun Yi, Kye-Hyung Kim
- Acute Crit Care. 2021;36(3):175-184. Published online August 12, 2021
- DOI: https://doi.org/10.4266/acc.2021.00409
- 5,951 View
- 309 Download
- 9 Web of Science
- 11 Crossref
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Abstract
PDF - Infections with multidrug-resistant organisms among patients in intensive care units (ICUs) are associated with high mortality. Among multidrug-resistant organisms, carbapenem-resistant Enterobacterales (CRE) harbor important pathogens for healthcare-associated infections, including pneumonia, bacteremia, and urinary tract infections. Risk factors for CRE colonization include underlying comorbid conditions, prior antibiotics exposure, prior use of healthcare facilities, device use, and longer ICU stay. The mortality rate due to invasive CRE infection is 22%–49%, and CRE colonization is associated with an approximately 10-fold increased risk of CRE infection. Infection control measures include hand hygiene, contact precautions, minimizing the use of devices, and environmental control. Additionally, implementing active surveillance of CRE carriage should be considered in ICU settings.
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Citations
Citations to this article as recorded by
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Scientific Reports.2024;[Epub] CrossRef - Identification and Preliminary Hierarchisation of Selected Risk Factors for Carbapenemase-Producing Enterobacteriaceae (CPE) Colonisation: A Prospective Study
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